The course introduces students to the:

• Monoclonal antibodies (mAb): production of murine, chimeric, humanized, human mAb (using phage display technology, transgenic animals and other technologies);
• Applications of mAb in the diagnostic and therapeutic biomedical field;
• Mechanisms of therapeutic antibody activity;
• Bispecific antibodies, BITEs and Single Chain Variable Fragments (scFv);
• Chimeric antigenic receptors (CARs) and cellular immunotherapy;
• Antibodies used in anti-inflammatory therapy and in immune pathologies;
• Antibodies used in cholesterol lowering therapy;
• Immune response to tumors and tumor immunotherapy;
• Antibodies active on proliferative and angiogenic signaling;
• Antibodies useful for activating anti-tumor immunity (CTLA-4 system, PD-1 PDL, others).
 
This course will be included in the curriculum.

Lecturers and developers: Prof., D.Sc. (Biology) Tetiana Filipova, senior researcher, PhD Korotaeva Nadiia